The effect PLACEBO and Mind, Conscience, Brain
Writing by bwerner on Friday, 11 of April , 2008 at 4:03 pm
Hello,
I want to introduce a series of articles regarding Mind Brain and Conscience
to give an understanding how we are made and how we can act against our personal problems by understanding our very nature of being. That will be four articles starting with the Placebo effect, followed by Mind Brain and Conscience 1-3. Since these articles are based up on scientific research that are going to be long and maybe compelling ones but knowledge is power and by having the power one is able to reach everything.
Enjoy your reading.
The effect PLACEBO & Mind, Conscience, Brain
“If we do not implement the Freedom of medical care in the constitution will come the time when medicine will organize, slowly and without being perceived, into a hidden Dictatorship. It’s the trying to restrict the art of medicine only to a class of people and the denial of equal privileges to the other “arts”, that will represent the Bastille of medical science “.
(By Benjamin Rush, signed the Declaration of Independence USA - 17 Sept 1787)
Flexner Report and Declaration of Alma Ata
Hidden Dictators (illegal) of medicine, on the other hand we know them very well… ..; they that dress clothes of the “barons” and “scientists”, which camouflage in the ” academic lobbies ” or operate in the multinationals of drugs, it is they who “count” and “govern” the official medicine.
At open minds and liberals the task of reacting to this mounting wave of anti-scientific intolerance, before these new tyrants even come to teach us what and what not is just right thinking…!
220 years later, this situation of health dictatorship has realized and you, dear reader, what are you doing to combat against it?
The F. D.A. (USA) has HIDDEN the EVIDENCE of the DANGER of TRANSGENIC FOOD
A study shows that infusions, pills (drugs) and Placebo, have the same therapeutic effect!
Herbs of S. John (great St John’s wort, hypericum) are useful against depression.
The study was published on “Jama”, which shows that the herbal remedy switch the bad mood completely to a quarter (25%), of those who take, such as sertraline (medicine), which is a known antidepressant “last generation”, widely used, with which it was compared!
The study, however, also included alongside the “placebo” that provided BETTER results on depressed, even 32%, much more than medicine and herbal remedies!
This study says a lot about how difficult it is to discern the reality of the effectiveness of “remedies and medicines” compared to the powers of self-healing of the sick person! Self-conviction + desire of healing = recovery of health!
In fact, it is to see how the patient feels in his own skin…
The belief that just a pill or a cure is enough triggers the mechanism of healing in some subjects more susceptible to these mechanisms!
The action of industrial pharmaceutical marketing, with the false advertising campaigns … who have advertised for decades… that the pill is enough to cure… has produced the loss in 68% in those who do not respond to this natural mechanism, of the self healing power.
The placebo effect (which generates the self-belief that he “assumed” something to heal) was also in the brain actions controlled with special equipment, and has shown that it radically changes the same centers, which should be the target of drugs/remedies.
This study demonstrates how it is impossible to demonstrate the effectiveness of antidepressant drugs and remedies for depression, invalidating of course, the credibility of the usefulness of drugs and remedies.
Depression has physical and psychological causes (sore of living or anxiety of living) that anyhow has to be researched and removed, that usually start by physical problems associated with the use of vaccines, drugs, dental amalgams and unsuitable food, altering and affecting the bacterial flora generating in turn serious intestinal malnutrition and cellular problems.
On placebo effect, which plays an important role also in the official medicine.
“It is not, as many argue, a psychological phenomenon,” explains Jon Kar Zubieta, a professor of psychiatry and radiology at the University of Michigan.
“It’s a physical phenomenon, scientifically proven and documented through diagnostic image techniques, such as PET (emission tomography positron) and MR (Magnetic Resonance), which photographs in real-time of the brain activity.”
Research has shown that the transmission of unpleasant feelings that in Medicine often correspond to illnesses, is a chemistry courier that from the nerve endings in the body and organs, passes the information cell to cell in the brain, where the feelings are labeled as “pain”, “itching” “nausea”, “cold”, “warm”.
This system is said “noceptive system”, that is the perception of unpleasant feelings. In parallel, however, there is another, “anti-noceptive” said, contrasting the unpleasant sensations. Here the actors are endorphins, opium similar substances produced naturally by the brain in areas destined to the perception of unpleasant feelings, which play a role in the “noceptive” chemistry couriers, reducing or even stopping the spread of negative messages. In particular, some receptors are the same on which act painkillers drugs.
In short, it does not matter much what fits into these receptors; the effect is always the same: reduce of unpleasant feelings.
USA Survey, 45% doctors cure with placebo.
January 3. 2008 (Adn kronos Health)
Those are medical interventions from which one expects no effect, because should not trigger any physiological mechanism. Nevertheless, they can get psychological reactions by the patient. To use at least once “placebo” in clinical practice was the 45% of internists in Chicago (USA), 466 of who were interviewed by researchers of the university of Midwest for a survey published on the ‘Journal of General Internal Medicine ‘.
The placebo is used in medicine since ancient times and today is used for experiments on drugs, but also in everyday practice. Within the sample of the Americans “white gowns” who confirmed that they use it, 34% consider placebo “a substance that can help the patient without harm”, for 19% it is anyway “a drug”, while 9% is convinced that it is “a medicine without specific effects.”
Among those who instead admits to not use this solution, 12% are convinced that we should prohibit it even categorically, especially because certain that the psychological reaction of a patient can affect the health. For these reasons, suggest the proponents a no vote, a valid alternative to the use of placebo could be meditation, yoga, relaxation techniques and prayer.
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Effect PLACEBO between science and mystery
interview with Fabrizio Benedetti on the strange effect and its implications.
Thirteen incomprehensible facts that resist to the explanation of scientists. Thirteen strange comments to which is devoted the front page of the “New Scientist” of 19 April 2005. To open the list, before the aliens messages, of the cold fusion or giants objects on the limits of the solar system, there is the placebo effect: the water cure (or sugar, secondly the cases).
Featured in first place in the story in New Scientist, together with placebo, is Fabrizio Benedetti, neurophysiologist of Turin. As reported by “Time Doctor” in the number 736 of 11 April 2002, for some considerable time the Italian scientist is dedicated to understand why in some clinical exams the pharmacologically inactive substances can have the same therapeutic efficacy of medicines of which represents the negative control. Time Doctor asked the protagonist to tell the mysteries and news on the placebo.
Thirteen scientific mysteries in the front row the placebo effect: what is so enigmatic into the object of his research work?
In reality, this is not a so mysterious work. My research group is occupied since ten years of placebo. Together, with other groups who interested in the rest of the world, have been clarified many aspects of this phenomenon. Perhaps that what is striking in that placebo effect is that it is rivaling to be an ideal model for studying the mind-brain relation. This is the challenge connoted by some mysterious: how can it happen that human mental expectation results in a cerebral physiological mechanism and measurable too?
And where do you in this challenge?
The question is still unanswered, but we continue to work of placebo for at least three distinct points of view: we study the mechanisms of neurophysiologically basis, we are trying to develop experimental protocols to test the effectiveness of drugs that do not contain the defect shape (and thus indirectly studying what could be called “placebo effect without placebo”) and try to apply the therapeutic benefits in clinical practice. The articles in New Scientist resumed on the first point of our research, whose latest news were published in Nature Neuroscience, in the June 2004. In particular, studies concerning the treatment of pain and treatment of Parkinson’s disease.
Your research showed the placebo effect also on some neurodegenerative diseases. Which in particular?
In the case of Parkinson’s, we tried to treat some patients for several days with drugs that reduce symptoms such as rigidity and tremors. These substances (e.g. L-Dopa and apomorphine), which mimic the action of dopamine, the neurotransmitter from calming deficient in these patients. Without warning patients at a certain point, we have replaced these substances with a saline solution without medicines and at the same time measured the activity of certain neurons of the sub thalamic nucleus, a hyperactive region in Parkinson’s patients. With the placebo, patients showed improvement in both, the motor as the reduction of neuronal activity: the saline solution produces really something in the brain.
And about the pain?
We have shown that in the treatment of pain with morphine, placebo induces the production of endogenous opium’s, endorphins. In fact, treatment with an opium antagonist, naloxone, produces the same effects for annulment of the effectiveness of treatment regardless of whether the patient is taking morphine or placebo. Therefore, a biochemical basis of the phenomenon exists, but as the mind actives, that remains a mystery.
In the meantime, we can exploit it to improve cure. This is the third line of research quoted before: taking advantage of the placebo to decrease the doses of drugs and reduce side effects and the likelihood of addiction. If the placebo works as morphine, one can imagine a therapy where every other day is administering the drug and placebo, reducing of 50 percent doses of morphine.
With regard to the second line on which deals with your research team: can you explain what it means to study the placebo effect without placebo?
The latest data we have collected are published on the number of “Lancet Neurology” in November 2004.
We tried to treat some patients suffering from various forms of pain, anxiety or from Parkinson’s disease, with active drugs in two ways: alerting the patient or administer them the drug without their knowledge, automatically through a computer. The main result is that the drug is less effective when the patient is very unaware of the treatment, while its effectiveness increases when the administered is aware, following the traditional medical practice. We believe that differences in the two treatment protocols are determined by the placebo effect, in this case is it produced without any substance placebo that is administered to the patient.
The use of hidden drug administration can form the basis for developing testing protocols deprived of psychological component. Moreover, the results confirm that the mere fact to undergo any form of therapy is beneficial to patients. Go to the doctor, be visited, get a prescription, follow the directions received, has a psychological effect on patients that strengthens their capacity of healing.
The lower effectiveness of hidden treatments indicates that the awareness of a cure will influence the chances of success and brings into the first place the importance of the doctor-patient relationship.
By Anna Piseri - Doctor No Time 794 - May 17, 2005
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The psychological healing.
The feedback on the deal, testifies to the validity of the placebo
In short: unconventional medicine, or not? Pulled at stake is the right of the patient to cure how he prefer, but certainly no society can afford the luxury of letting die its members: fashions come and go, the civil and criminal liability remain, in addition to the social costs that this entails not faceable.
The scientific evidence, in the present state of knowledge, are all against unconventional drugs and therapies, though dutifully evaluated according to rigid standards, even conventional therapies cover a broad spectrum ranging from saving to lethal, passing through varying degrees of uselessness. In both cases there are to be considered enormous commercial interests, who profits from these markets want to survive, and then try to tilt the balance into its own favor. If you do not play in both camps, to be sure.
The Royal Homoeopathic Hospital in London performs nearly 30,000 visits a year, in exclusive homeopathic system, and is sponsored by the Crown: there seems not to be a problem; indeed, expenditure by the National Britain Health Service has proved to be very low.
Placebo effect? It can be. Meanwhile, however, people really heal, and if a placebo effect on end balance heals almost as many patients as from drugs, perhaps it would be better to study the mechanisms.
It is commonly agreed, for example, that this is not just imagination: the body of the patient, whether he is an adult, a child, an animal or even a plant (it’s not known in what way), reacts to treatment when it realize, became convinced of being cured. It activates a process, often effective, of self-healing.
Comment: The Natural Medicine shows that the remedies and/or infusions are NOT sufficient alone to establish the processes of bodily healing, but we must activate various naturally techniques, taught from it, and that contemporarily and/or after the recruitment of remedies and/or infusions.
NE drug, remedies and/or infuses that heals, but it is all in addition to the various techniques Psychological = Spiritual (the research for the path of healing), which necessarily must be put into practice on themselves, what used to obtain the desired effect, and/or maintain their health!
Recommended also to monitor and search any possible existing Nano- particle that can affect the processes of placebo!
However, one thing is established, the effectiveness of Placebo!
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Also the allopathic Doctors use the placebo effect.
21 January 2007. A young medical student of the University of Chicago, Rachel Sherman, is engaged in a survey to assess the frequency of prescriptions of placebo, i.e. inactive medication, and the reasons why American doctors use it. With the help of a professor, they sent a questionnaire to 466 specialists in internal medicine of the three largest university hospitals of Michigan. The results are on “Journal of General Internal Medicine” in January 2008.
The surprising thing is that 45% of hospital doctors questioned use the virtue of placebo. They do it when the complaints of patients are inaccurate or they do request for “unjustified” medicine, or to control pain.
It is obvious the ability of self-healing of the people, which explains many phenomena of healing attributed to the so-called miracles.
By Primo Mastrantoni, secretary Aduc.
Rachel Sherman, a 4th year medical student at the University of Chicago’s Pritzker School of Medicine, and Dr. John Hickner, a professor of family medicine at the University of Chicago and University of Chicago Medical Center.
www.medicalnewstoday.com/articles/93003.php
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If the placebo costs more ‘is it’ more effective…
Researchers of the Duke University have found that a patient is more inclined to consume a more expensive drug. An attitude that may have a result on the effective therapy.
Research shows that a pill from 15 cents would be a less appreciated than one that costs 3 dollars, at least if in both cases it is placebo.
For the research, led by Dr. Ariel and colleagues from the Massachusetts Institute of Technology, have been summoned 82 volunteers. They were subjected to a standard protocol that included the use of an electric shock to see the variable sensitivity to the subjective sensation of pain before and after taking the placebo.
Participants were divided into two groups: one group was given a written explanation about the benefits of a new drug whose anti-painful cost moved about 3 dollars; to another group the same written explanation mentioned a new anti-painful whose price each dose was only 10 cents, without further explanation as to why such a low cost.
The result of the test showed that the reduction in symptoms of pain after taking the placebo were monitored, in 85 percent of participants in the first group, and 61 percent of the participants belonging to the second group.
Source: Journal of the American Medical Association (JAMA) - March 2008
With kindly permission of www.mednat.org
Category: Health, Personal Development, Science
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